Covered Mutations

BRAF V600: The Assay is intended for identification of the mutations V600D/E/K/R in the BRAF gene.

KRAS: The assays identify 23 mutations in KRAS exon 2, 3 and 4. They are made for identification of mutations in codons 12, 13, 59, 61, 117 and 146 of the KRAS gene.

KIT: This assay identifies the aspartic acid (D) to valine mutation in codon 816 of the KIT gene (D816V).  

NRAS: The assays identify 24 mutations in NRAS exon 2, 3 and 4. The assays are intended for identification of mutations in codons 12, 13, 59, 61, 117 and 146 of the NRAS gene.

PIK3CA H1047:  The assays identify three mutations in codon 1047.

The assays are intended for identification of the mutations H1047L/R/Y in the PIK3CA gene.